Mark Cuban has some interesting thoughts in My New Facebook Strategy and the FB Power Level on managing large social networks and the opportunity - and limits - of using those connections:
The 3rd layer is emerging as a very unique and interesting network in FB. Its what I will call “The Power Layer.” These are people who in whatever industry they are in , retain some level of power. Having them as FB friends, although very simple and non committal, gives me some level of access to them, and them to me. These are people that if they sent me a FB mail, i would certainly read and respond to , and I think they would do the same.
Its what I could also call the one shot layer. If you have an idea or thought, you get 1 shot, per year to get their attention. Anything more than that probably could and would get me deleted. Everyone at this layer gets pitched continuously. Myself included. If you abuse it, you lose it.